中国医科大学学报

中国医科大学学报
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中国医科大学学报 ›› 2017, Vol. 46 ›› Issue (11): 1032-1035.doi: 10.12007/j.issn.0258‐4646.2017.11.016

• 论著 • 上一篇    下一篇

预防性给予止吐药物的妇科患者发生术后恶心呕吐的 危险因素

梁晨曦,刘丽丹,穆莹,冯静,张宁,吴秀英   

  1. 中国医科大学附属盛京医院麻醉科,沈阳 110004
  • 收稿日期:2017-02-27 出版日期:2017-11-30 发布日期:2017-11-01
  • 通讯作者: 吴秀英 E-mail:wuxy@sj-hospital.org
  • 作者简介:梁晨曦(1992-),女,硕士研究生

Risk Factors for Postoperative Nausea and Vomiting in Gynecological Patients Administered Prophylactic Antiemetics

LIANG Chenxi,LIU Lidan,MU Ying,FENG Jing,ZHANG Ning,WU Xiuying   

  1. Department of Anesthesiology,Shengjing Hospital,China Medical University,Shenyang 110004,China
  • Received:2017-02-27 Online:2017-11-30 Published:2017-11-01

摘要: 目的 研究预防性给予止吐药物的妇科患者发生术后恶心呕吐(PONV)的危险因素。方法 选择行妇科手术的患者1 000例,收集患者基本资料以及麻醉、手术和其他资料,并于术后第1天进行恶心呕吐的调查随访,对数据进行统计学分析。结果 多因素logistic回归分析纳入晕动病史、镇痛泵、麻醉时长、术毕应用新斯的明,按OR值从大到小排序为晕动病史(OR=1.953,95% CI:1.404~2.716)、术毕应用新斯的明(OR=1.831,95%CI:1.203~2.786)、镇痛泵(OR=1.472,95% CI:1.017~2.129)、麻醉时长(OR=1.256,95% CI:1.058~1.492),预测模型为 。此模型判断妇科患者PONV的准确度为70.6%, 预测结果ROC曲线下面积为0.642。结论 预防性给予止吐药物的妇科患者发生PONV的独立危险因素按影响程度由大到小为 晕动病史、术毕应用新斯的明、镇痛泵、麻醉时长。

关键词: 术后恶心呕吐, 妇科手术, logistic回归分析

Abstract: Objective To study the risk factors for postoperative nausea and vomiting(PONV)in gynecological patients administered prophylactic antiemetics. Methods A total of 1 000 gynecological surgical cases were reviewed. Data on patient characteristics,anes- thesia,surgeries,and 1st postoperative day nausea and vomiting were collected and analyzed statistically. Results Multivariate logistic regression analysis included a history of motion sickness,the use of an analgesic pump,the duration of anesthesia,and the use of neostig- mine. The odds ratios(ORs),in decreasing order,were that of a history of motion sickness[OR = 1.953,95% confidence interval(CI):1.404 - 2.716],the use of neostigmine(OR = 1.831,95% CI:1.203 - 2.786),the use of an analgesic pump(OR = 1.472,95% CI:1.017-2.129),and the duration of anesthesia(OR = 1.256,95% CI:1.058 - 1.492). The predictive model was described by the following equation: . The predictive accuracy of this model for the incidence of PONV in gynecological patients was 70.6%,and the area under the receiver operating characteristic curve for the predictive result was 0.642. Conclusion The independent risk factors for PONV in gynecological patients administered prophylactic antiemetics are a history of motion sickness,the use of neostig- mine,the use of an analgesic pump,and the duration of anesthesia,in decreasing order of significance.

Key words: postoperative nausea and vomiting, gynecological surgery, logistic regression analysis

中图分类号: 

  • R614.2
[1] 万静洁,李真,金宁,滕秀飞,张焕焕,朱俊超. 小剂量七氟醚或笑气复合丙泊酚对宫腔镜术后恶心呕吐的影响[J]. 中国医科大学学报, 2016, 45(1): 77-79.
[2] 韩婧楠,万超,赵宁,刘宁宁,柳力敏,才娜,陈蕾. 玻璃体切割术后眼压升高危险因素的临床分析[J]. 中国医科大学学报, 2015, 44(5): 429-433.
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