中国医科大学学报

中国医科大学学报
  • 中文核心期刊
  • 中国科技核心期刊
  • 中国高校百佳科技期刊
  • BA、CA收录

中国医科大学学报 ›› 2018, Vol. 47 ›› Issue (6): 542-547.doi: 10.12007/j.issn.0258‐4646.2018.06.014

• 论著 • 上一篇    下一篇

慢性阻塞性肺疾病、尘肺患者生活质量及其影响因素分析

朱春明1, 张鹤1, 刘红波2, 郑锐1   

  1. 1. 中国医科大学附属盛京医院呼吸内科, 沈阳 110022;
    2. 中国医科大学公共卫生学院卫生统计学教研室, 沈阳 110122
  • 收稿日期:2017-12-28 出版日期:2018-06-30 发布日期:2018-05-29
  • 通讯作者: 郑锐 E-mail:zhengr@sj-hospital.org
  • 作者简介:朱春明(1987-),男,医师,硕士研究生.
  • 基金资助:
    辽宁省临床能力建设项目(LNCCC-D14-2015)

Analysis of Health-related Quality of Life and Its Influencing Factors in Patients with Chronic Obstructive Pulmonary Disease and Pneumoconiosis

ZHU Chunming1, ZHANG He1, LIU Hongbo2, ZHENG Rui1   

  1. 1. Department of Respiratory Medicine, Shengjing Hospital, China Medical University, Shenyang 110022, China;
    2. Department of Health Statistics, School of Public Health, China Medical University, Shenyang 110122, China
  • Received:2017-12-28 Online:2018-06-30 Published:2018-05-29

摘要: 目的 比较慢性阻塞性肺疾病(COPD)与尘肺患者生活质量及影响因素。方法 对101例COPD患者(COPD组)及91例尘肺患者(尘肺组)进行SGRQ评分及肺功能测定,收集相关资料,分析2组患者生活质量及影响因素,运用多元回归法校正相关影响因素后进一步对2组患者生活质量进行比较。结果 在年龄无统计学差异情况下,COPD组患者呼吸症状得分高于尘肺组(P<0.05);其余维度及SGRQ总分2组差异无统计学意义(P>0.05);多元分析结果显示,校正相关混杂因素后COPD组患者呼吸症状得分仍高于尘肺组(P<0.05)。结论 COPD与尘肺患者生活质量差异不显著,生活质量影响因素存在差异,在年龄及通气功能近似情况下COPD患者呼吸症状较尘肺患者更重。

关键词: 尘肺, 慢性阻塞性肺疾病, 生活质量, 影响因素

Abstract: Objective To compare the health-related quality of life (HQOL) of patients with pneumoconiosis and chronic obstructive pulmonary disease (COPD), and to explore whether there are differences between the two groups in terms of factors influencing HQOL. Methods We included 101 patients with COPD and 91 patients with pneumoconiosis. The two groups were compared based on St. George's respiratory questionnaire (SGRQ) scores, lung function measurements, and HQOL differences. Moreover, the correlation between various factors and HQOL was analyzed. Results Age was comparable between the two groups. The respiratory symptom scores of patients with COPD were significantly higher than those of patients with pneumoconiosis (P<0.05). There were no significant differences between the groups in the other SGRQ dimensions or the total score. After adjusting for possible confounding factors, the respiratory symptoms of patients with COPD remained significantly higher than those of patients with pneumoconiosis (P<0.05). Conclusion There was no significant difference in HQOL between patients with COPD and those with pneumoconiosis. The main influencing factors of HQOL differed between the two groups. The respiratory symptoms of patients with COPD were more severe than those of patients with pneumoconiosis when controlling for age and ventilatory function.

Key words: pneumoconiosis, chronic obstructive pulmonary disease, health-related quality of life, influencing factor

中图分类号: 

  • R562
[1] GAGNON P,GUENETTE JA,LANGER D,et al. Pathogenesis of hyperinflation in chronic obstructive pulmonary disease[J]. Int J Chron Obstruct Pulmon Dis,2014,9:187-201. DOI:10.2147/COPD. S38934.
[2] 钟学飘,朱志良,马争,等.2005-2013年全国职业病发病情况分析[J].实用预防医学,2015,22(7):858-859. DOI:10.3969/j.issn.1006-3110.2015.07.030.
[3] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2013年修订版)[J].中华结核和呼吸杂志,2013, 36(4):255-264. DOI:10.3760/cma.j.issn.1001-0939.2013.04.007.
[4] LIU HB,YAN B,HAN B,et al. Determination of ameliorable health impairment influencing health-related quality of life among patients with silicosis in China:a cross-sectional study[J]. J Int Med Res, 2011,39(4):1448-1455. DOI:10.1177/147323001103900433.
[5] JONES PW,QUIRK FH,BAVEYSTOCK CM,et al. A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire[J]. Am Rev Respir Dis,1992, 145(6):1321-1327. DOI:10.1164/ajrccm/145.6.1321.
[6] CHUNDAK TS,STEVEN LL,SHAKUNTALA S,et al. Validation of the St. George's respiratory questionnaire in Nepal[J]. Chronic Obstr Pulm Dis,2015,2(4):281-289. DOI:10.15326/jcopdf.2.4.2014.0156.
[7] 郑乐贵,徐显,李继法,等. COPD老年患者病情严重程度与生活质量的相关性[J].中国老年学杂志,2015,35(1):35-37. DOI:10.3969/j.issn.1005-9202.2015.01.017.
[8] DOMINGO-SALVANY A,LAMARCA R,FETTER M,et al. Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease[J].Am J Respir Crit Care Med,2002, 166(5):680-685. DOI:10.1164/rccm.2112043.
[9] GUDMUNDSSON G,GISLASON T,JANSON C,et al.Risk factors for rehospitalisation in COPD:role of health status,anxiety and depression[J]. Eur Respir J,2005,26(3):414-419. DOI:10.1183/09031936.05.00078504.
[10] SWIGRIS JJ,ESSER D,CONOSCENTI CS,et al. The psychometric properties of the St George's respiratory questionnaire (SGRQ) in patients with idiopathic pulmonary fibrosis:a literature review[J]. Health Qual Life Outcomes,2014,12(1):124. DOI:10.1186/s12955-014-0124-1.
[11] TANG WK,LUM CM,UNGVARI GS.Health-related quality of life in community-dwelling men with pneumoconiosis[J]. Respiration, 2006,73(2):203-208. DOI:10.1159/000088681.
[12] TANG WK,LUM CM,UNGVARI GS. Alcohol consumption,lung function,and quality of life in pneumoconiosis[J]. Alcohol Clin Exp Res, 2005,29(7):1230-1236. DOI:10.1097/01.ALC.0000171939.49477.6B.
[13] 阎波,韩冰,孙金凯.壹期尘肺患者生命质量状况调查与分析[J]. 中国工业医学杂志,2011,24(5):373-375.
[14] 李扬.老年COPD患者健康相关生活质量及影响因素研究概况[J].云南大学学报(自然科学版),2009,31(S1):387-395.
[15] BERRY CE,DRUMMOND MB,HAN MK,et al. Relationship between lung function impairment and health-related quality of life in COPD and interstitial lung disease[J]. Chest,2012,142(3):704-711. DOI:10.1378/chest.11-1332.
[16] MARTIN AL,JESSICA M,KYLE F,et al. The association of lung function and St. George's respiratory questionnaire with exacerbations in COPD:a systematic literature review and regression analysis[J]. Respir Res,2016,17(1):1-15. DOI:10.1186/s12931-016-0356-1.
[17] ELCI A,BOREKCI S,OVAYOLU N,et al. The efficacy and applicability of a pulmonary rehabilitation programme for patients with COPD in a secondary-care community hospital[J]. Respirology, 2008,13(5):703-707. DOI:10.1111/j.1440-1843.2008.01327.x.
[18] JOLLY K,MAJOTHI S,SITCH AJ,et al. Self-management of health care behaviors for COPD:a systematic review and meta-analysis[J]. Int J Chron Obstruct Pulmon Dis,2016,11:305-326. DOI:10.2147/COPD.S90812. eCollection 2016.
[19] SCIRIHA A,LUNGARO-MIFSUD S,SCERRI J,et al. Health status of COPD patients undergoing pulmonary rehabilitation:A comparative responsiveness of the CAT and SGRQ[J]. Chron Respir Dis, 2017,14(4):352-359. DOI:10.1177/1479972317694622.
[20] 刘春云,肖新发,陈谦,等.尘肺患者呼吸功能及全身营养状态与疾病严重程度的相关性研究[J].医学理论与实践,2014,27(11):1405-1406.
[1] 夏天慧, 范玲. 沈阳市社区老人居家养老护理需求现状分析[J]. 中国医科大学学报, 2018, 47(7): 649-654.
[2] 王雅娟, 郭艳霞. 延续性护理对帕金森病患者出院后生活质量的影响[J]. 中国医科大学学报, 2018, 47(7): 663-665.
[3] 李艳, 李晓飞, 谢琳, 邵龙, 董赢. 沈阳市三级甲等医院护士睡眠质量调查及影响因素分析[J]. 中国医科大学学报, 2018, 47(7): 666-669.
[4] 朱春明, 张鹤, 郑锐. 中性粒细胞/淋巴细胞比值、红细胞分布宽度与慢性阻塞性肺疾病急性加重的相关分析[J]. 中国医科大学学报, 2018, 47(4): 312-315.
[5] 刘力, 孙清雨. 草酸艾司西酞普兰治疗乳腺癌伴抑郁症患者的效果[J]. 中国医科大学学报, 2018, 47(11): 1021-1024.
[6] 王爱平, 刘海丽, 姜楠. 护士职业价值取向及影响因素研究[J]. 中国医科大学学报, 2018, 47(11): 1043-1046.
[7] 王东博, 华明蕊, 潘悦达, 白咏梅, 韩德民. 护士焦虑现况及影响因素分析[J]. 中国医科大学学报, 2018, 47(10): 921-923,928.
[8] 王思博,王慧彬,曲慧玲,赵珊珊,赵传胜. 卒中后抑郁的影响因素及其对生活质量的影响[J]. 中国医科大学学报, 2017, 46(9): 844-847.
[9] 奚奇,万成福,刘妍,于雪,董道松,赵林,宋涛. 马来酸氟吡汀对带状疱疹后三叉神经痛常规治疗的影响[J]. 中国医科大学学报, 2017, 46(7): 660-663.
[10] 张云,刘宏娟. 医学生心理健康水平现状及其影响因素的调查分析[J]. 中国医科大学学报, 2017, 46(4): 335-338.
[11] 孙叶飞 ,詹娇阳. 循证护理干预对脑梗死后继发癫痫患者治疗依从性及生活质量的影响[J]. 中国医科大学学报, 2017, 46(4): 377-379.
[12] 王平,单忠艳,姜雅秋. 217 例 2 型糖尿病住院患者血糖波动的影响因素[J]. 中国医科大学学报, 2017, 46(3): 244-247.
[13] 赵辉,杨国峰. 综合护理措施在硫酸沙丁胺醇气雾剂吸入治疗慢性阻塞性肺疾病中的作用[J]. 中国医科大学学报, 2017, 46(2): 184-186.
[14] 刘江伟,赵立,朱丽华,王娜,孙朋波. 气流受限不完全可逆的慢性阻塞性肺疾病患者容量和 流速变化与肺通气功能障碍严重程度分级的关系[J]. 中国医科大学学报, 2016, 45(9): 805-808.
[15] 李敏,崔雪娇,李玉姝,左迪,安娜. Graves眼病患者生活质量及眼病特异性生活质量的相关性[J]. 中国医科大学学报, 2016, 45(5): 445-447.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!

中国医科大学学报版权所有©2018

未经允许,严禁擅自转载本站图文资料

地址:中国 沈阳市沈北新区蒲河路77号 110122

辽ICP备05014850

JOURNAL OF CHINA MEDICAL UNIVERSITY

ADDRESS: NO.77 PUHE ROAD

SHENYANG NORTH NEW AREA, SHENYANG

LIAONING PROVINCE, P.R. CHINA