中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2015, Vol. 44 ›› Issue (12): 1057–1060.doi: 10.12007/j.issn.0258-4646.2015.12.001

• 论著 •    下一篇

利用频域光学相干断层扫描测量青光眼视盘旁萎缩区

马小力,刘贤洁,陈禹橦,李丹丹,张宏伟,华瑞   

  1. 中国医科大学附属第一医院眼科,沈阳110001
  • 收稿日期:2015-09-17 出版日期:2015-12-15 发布日期:2015-12-17
  • 通讯作者: 华瑞,E-mail:woodshua@126.com
  • 作者简介:马小力(1978 -),女,副教授,博士
  • 基金资助:

    国家自然科学基金(81200656);辽宁省博士启动基金(20111097)

Application of Spectral-domain Optical Coherence Tomography for Measuring Peripapillary Atrophy in Glaucoma

MA Xiaoli,LIU Xianjie,CHEN Yutong,LI Dandan,ZHANG Hongwei,HUA Rui     

  1. DepartmentofOphthalmology,TheFirstHospital,ChinaMedicalUniversity,Shenyang110001,China
  • Received:2015-09-17 Online:2015-12-15 Published:2015-12-17

摘要:

目的 利用频域光学相干断层扫描(SD-OCT)和眼底彩色照相方法测量青光眼视盘旁萎缩区,并比较二者结果的一致性。方法 连续收集就诊于中国医科大学附属第一医院眼科的青光眼患者30例(54只眼),进行视盘SD-OCT检查和眼底彩色立体照相。分别测量以视盘为中心6条子午线上视盘旁萎缩区β区宽度并计算平均值,比较2种检查结果的相关性,并进行一致性评价。结果 使用眼底彩色照相法和SD-OCT检查法测量青光眼患者眼底视盘旁萎缩区β区平均宽度分别为229.89±99.82)μm和(224.14±97.10)μm,二者比较无统计学差异(P = 0.280)。2种检查方法结果具有高度相关性(r = 0.825,P < 0.001),二者间具有良好的一致性(ICC=0.923,95% CI 0.870~0.954)。结论 利用SD?OCT法与眼底彩色照相法测量青光眼视盘旁萎缩区β区结果具有良好的一致性,可以利用SD-OCT方法测量青光眼视盘旁萎缩区β区。

关键词: 青光眼, 视盘旁萎缩区, 频域光学相干断层扫描

Abstract:

Objective To measure peripapillary atrophy(PPA)in glaucoma with high-resolution spectral domain-optical coherence tomography (SD-OCT)and conventional color fundus photograph,and compare the consistency of the results between the two imaging methods. Methods A total of 30 patients(54 eyes)with glaucoma from Department of Opthalmology,the First Hospital,China Medical University were prospectively included for the study. SD-OCT images and color fundus photographs taken through the region of PPA were qualitatively analyzed. The average width of β-PPA area in 6 reference lines centered optic nerve were measured using SD-OCT and color fundus photograph. Correlation and agreement between the two measuring methods were analyzed. Results The average width of β-PPA was 229.89±99.82 μm using color fundus photographs and 224.14±97.10 μm using SD-OCT,respectively. There was no significant difference(P = 0.280). The correlation coefficient was 0.825 between results measured by SD?OCT and color fundus photographs for β-PPA area(P < 0.001),and agreement between the two methods was good(ICC=0.923,95% CI 0.870-0.954). Conclusion The correlation and consistency is good between SD-OCT and conventional color fundus photograph measuring β-PPAarea.β-PPA area can bee stimated with SD-OCT.

Key words: glaucoma, peripapillary atrophy, spectral domain?optical coherence tomography

中图分类号: 

  • R775
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[3] 马小力,陈禹橦,刘贤洁,李丹丹,张宏伟,宁宏. 频域光学相干断层扫描测量黄斑区视网膜神经节细胞层厚度[J]. 中国医科大学学报, 2016, 45(5): 389-393.
[4] 马小力,陈禹橦,刘贤洁,李丹丹,张宏伟,宁宏. 频域光学相干断层扫描测量青光眼视网膜神经纤维层厚度的可重复性研究[J]. 中国医科大学学报, 2016, 45(3): 197-200.
[5] 尚琢, 彭程, 赵芳坤, 刘野, 赵江月, 张劲松. 心理干预对青光眼患者生活质量的影响[J]. 中国医科大学学报, 2012, 41(2): 190-190.
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