中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2016, Vol. 45 ›› Issue (3): 264–268.doi: 10.12007/j.issn.0258-4646.2016.03.018

• 论著 • 上一篇    下一篇

斑点追踪成像结合实时心肌超声造影对心肌不同灌注状态的评价

蒋媛媛 1,徐洋 2,任卫东 3   

  1. 1厦门大学附属第一医院超声科,福建 厦门 361001;2厦门大学附属第一医院整形外科,福建 厦门 361001;3中国医科大学附属盛 京医院超声科,沈阳 110004
  • 收稿日期:2015-07-27 出版日期:2016-02-29 发布日期:2016-02-24
  • 通讯作者: 任卫东 E-mail:E-mail:renwd01@163.com
  • 作者简介:蒋媛媛(1980 -),女,医师,博士.

Evaluation of Different Perfusion Status of Myocardium Using Speckle Tracking Imaging and Real-time Myocardial Contrast Echocardiography

JIANG Yuan-yuan1,XU Yang2,REN Wei-dong3   

  1. 1Department of Ultrasound,The First Affiliated Hospital of Medicine,Xiamen University,Xiamen 361001,China;2Department of Plastic Surgery,The First Affiliated Hospital of Medicine,Xiamen University,Xiamen 361001,China;3Department of Ultrasound,Shengjing Hospital,China Medical University,Shenyang 110004,China
  • Received:2015-07-27 Online:2016-02-29 Published:2016-02-24

摘要: 目的 定量评价急性心肌梗死(AMI)经皮冠状动脉介入治疗(PCI)术前、术后左心室局部心肌功能和心肌灌注的动态变 化。方法 选取 48 例接受 PCI 手术治疗的 1 周内 AMI 患者(治疗组)和 30 例健康志愿者(对照组),采用斑点追踪成像(STI)及实 时心肌超声造影(RT-MCE)技术评价 PCI 手术前后局部纵向应变及心肌灌注变化特征,并与单光子发射计算机断层扫描术(SPECT)结果进行相关性分析。结果 PCI 术前,治疗组各应变和灌注指标均较对照组明显降低。PCI 术后 1 个月,与术前比 较,除部分心肌节段心肌造影剂灌注速率无改善外,其他各指标均明显升高,差异有统计学意义(P < 0.05);术后 1 个月,左心室 局部纵向峰值应变、心肌灌注达峰强度和局部心肌血流量与单光子发射计算机断层成像术的心肌灌注量呈正相关(r 分别为0.75、0.72、0.76,均 P < 0.05)。结论 STI 技术结合 RT-MCE 技术能够准确评价 AMI 患者 PCI 手术前后的左心室局部功能和心肌 灌注的变化特征。

关键词: 斑点追踪成像, 实时心肌超声造影, 心肌梗死

Abstract: Objective To quantitatively evaluate the left ventricular regional myocardial function and myocardial perfusion in patients with acute myocardial infarction(AMI)before and after percutaneous coronary intervention(PCI)using speckle tracking imaging(STI)and real-time myocardial contrast echocardiography(RT-MCE). Methods LV length-axis images were acquired in 48 patients with AMI who underwent successful PCI within 1-month of AMI onset(treatment group),as well as 30 healthy individuals as control group. Conventional echocardiography,STI and RT- MCE were done in both 2 groups before and 1 month after PCI. The correlation analysis between the above index and single-photon emission comput- ed tomography(SPECT)after PCI 1 month was also studied. Results Before PCI,a severe reduction in strain and perfusion was observed in treatment group compared to the control group. One month after PCI,there were obvious changes in strain and perfusion index in treatment group,except partial myocardial region in K.Even. Although there were markedly improvement of the most index,significant differences were found between the two groups(P < 0.05). One month post operation,local longitudinal peak strain of left ventricular,myocardial perfusion of peak intensity and regional myocardial blood flow were positively correlated with single photon emission computed tomography amount of myocardial perfusion imaging(SPECT)(r were 0.75,0.72,0.76,P < 0.05). Conclusion STI combined with RT-MCE can accurately evaluate the regional myocardial motion and perfusion of AMI patients before and after PCI and can monitor the improvement of myocardial function after revascularization.

Key words: speckle tracking imaging, real-time myocardial contrast echocar diography, myocardial infarction

中图分类号: 

  • R540.45
[1] 武佳科, 田春阳, 何东旭, 宋佳, 于彤彤, 孙志军, 孙兆青. 休克指数对行经皮冠状动脉介入治疗的急性心肌梗死患者长期预后的预测价值[J]. 中国医科大学学报, 2018, 47(6): 522-526.
[2] 杜守治 ,董斌 ,齐中华. 急性心肌梗死和急性脑梗死 miRNA 疾病标志物的初步筛查[J]. 中国医科大学学报, 2017, 46(8): 681-685.
[3] 刘鹏飞 ,张海涛 ,齐弘炜 王楠楠 ,张博阳 ,袁彪 ,李田昌. 过表达 microRNA-486 对大鼠心肌梗死后心脏功能损伤的改善[J]. 中国医科大学学报, 2017, 46(7): 595-599.
[4] 王晓冰,杨军,陈昕,马春燕. 左心室纵向应变预测原发性二尖瓣反流术后左心室收缩功能减低[J]. 中国医科大学学报, 2017, 46(4): 353-356.
[5] 朱家赫,于彤彤,孙兆青. 完全血运重建策略对老年急性 ST 段抬高型心肌梗死合并多支 血管病变患者预后的影响[J]. 中国医科大学学报, 2017, 46(3): 227-231.
[6] 李春华,徐萍. 行经皮冠状动脉介入术的急性心肌梗死患者的围术期护理[J]. 中国医科大学学报, 2017, 46(2): 181-183.
[7] 严宁,张华,赵小瑞,黄晖,丛广志,陈大鹏,沙勇,贾绍斌. 青年回、汉族急性心肌梗死患者临床特点及冠脉病变特征分析[J]. 中国医科大学学报, 2015, 44(5): 452-455.
[8] 王勇,王琦,柳兢,周东晖,金元哲. 直接支架植入在急性心肌梗死急诊PCI中的临床应用[J]. 中国医科大学学报, 2015, 44(5): 468-471.
[9] 刘君,雷明明,王妍,金元哲. FKN在急性心肌梗死早期诊断中的作用[J]. 中国医科大学学报, 2015, 44(4): 307-310.
[10] 彭帆,,刘闺男. 老年STEMI伴高尿酸血症患者冠状动脉病变特点分析[J]. 中国医科大学学报, 2015, 44(4): 338-341.
[11] 杨洋,李潞,侯平,东洋,杜秋红,杨蕾,徐萍. 收缩压、脉压、循环microRNA与急性心肌梗死的相关性[J]. 中国医科大学学报, 2015, 44(11): 1017-1020.
[12] 于艳丽,黄家中,李悦,于彤彤,刘兴利,庞文跃,孙志军,孙兆青. 40岁以下青年急性心肌梗死患者临床特点分析[J]. 中国医科大学学报, 2015, 44(1): 77-80.
[13] 余惠珍,朱鹏立,黄舒洁,向红,潘玮,张枫,林帆. 组织激肽释放酶改善大鼠心肌重塑的实验研究[J]. 中国医科大学学报, 2014, 43(9): 830-835.
[14] 王晓冰,陈昕,马春燕,杨军. 二维斑点追踪成像评价原发性二尖瓣反流患者左室收缩功能隐匿性减低[J]. 中国医科大学学报, 2014, 43(8): 682-685.
[15] 马晶茹,金霞,谭力力,李飞,张继红. 急性广泛前壁心梗患者介入手术中和术后重组人脑利钠肽干预的研究[J]. 中国医科大学学报, 2014, 43(7): 602-605.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!

中国医科大学学报版权所有©2018

未经允许,严禁擅自转载本站图文资料

地址:中国 沈阳市沈北新区蒲河路77号 110122

辽ICP备05014850

JOURNAL OF CHINA MEDICAL UNIVERSITY

ADDRESS: NO.77 PUHE ROAD

SHENYANG NORTH NEW AREA, SHENYANG

LIAONING PROVINCE, P.R. CHINA