中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2016, Vol. 45 ›› Issue (5): 445–447.doi: 10.12007/j.issn.0258-4646.2016.05.016

• 论著 • 上一篇    下一篇

Graves眼病患者生活质量及眼病特异性生活质量的相关性

李敏,崔雪娇,李玉姝,左迪,安娜   

  1. 中国医科大学附属第一医院内分泌科,沈阳 110001
  • 收稿日期:2016-01-13 出版日期:2016-05-30 发布日期:2016-05-09
  • 作者简介:李敏(1978 -),女,主管护师,硕士.
  • 基金资助:
    中华医学会内分泌分会临床医学科研专项基金(201209)

Relationship between the Health-related Life Quality and Graves′Ophthalmopathy Quality of Life in Graves′Ophthalmopathy Patients

LI Min,CUI Xuejiao,LI Yushu,ZUO Di,AN Na   

  1. Department of Endocrine Medicine,The First Hospital,China Medical University,Shenyang 110001,China
  • Received:2016-01-13 Online:2016-05-30 Published:2016-05-09

摘要: 目的 评估 Graves 眼病(GO)患者的生活质量与眼病活动度、甲状腺自身抗体等的相关性。方法以 SF-36 量表及眼病特异性生活质量量表(GO-QOL)调查 44 例 GO 患者的生活质量评分,检测患者的甲状腺功能、相关抗体水平及疾病活动度评分。结果 年龄>45 岁的 GO 患者 SF-36 评分、GO-QOL 评分显著低于年龄≤45 岁的患者(P < 0.05)。促甲状腺激素受体抗体(TRAb)>10 IU/mL 的患者 GO-QOL 评分及其中的社会心理评分低于 TRAb≤10 IU/mL 的患者(P < 0.05)。GO 眼病活动度评分≥3 分的患者 SF-36 评分和 GO-QOL 评分均显著低于眼病活动度评分<3 分的患者(均 P < 0.01)。结论 GO 患者眼病特异性的生活质量降低,降低程度与年龄、TRAb 水平和眼病活动度相关。

关键词: Graves 眼病, Graves 眼病, SF-36, SF-36, 甲状腺相关眼病生活质量, 甲状腺相关眼病生活质量

Abstract: Objective To study the relationship between the health-related quality of life and Graves′ophthalmopathy quality of life(GO-QOL)in Graves′ophthalmopathy(GO)patients. Methods A total of 44 GO patients were recruited for the study and investigated with SF-36 and GO-QOL questionnaires. In addition,the thyroid function and related antibodies were also detected. Results The scores of SF-36 and GO-QOL were higher in the patients over 45 years than those under 45 years(P < 0.05). GO-QOL score was lower in the patients with thyroid stimulating hormone receptor antibody higher than 10 IU/mL(P < 0.05). The scores of SF-36 and GO-QOL were obviously higher in the patients who had a clinical activity score above 3(P < 0.01). Conclusion GO-QOL is a better and more specific questionnaire for GO patients.

Key words: Graves′ophthalmopathy, Graves′ophthalmopathy, SF-36, SF-36, Graves′ophthalmopathy quality of life, Graves′ophthalmopathy quality of life

中图分类号: 

  • R581.1
[1] 姚鹏,李泓锡,王志彬,洪涛,朱永强,马佳明,丁远远. 较低温度局麻下射频热凝术治疗三叉神经痛的有效性[J]. 中国医科大学学报, 2016, 45(11): 1006-1012.
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