中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2016, Vol. 45 ›› Issue (10): 923–925.doi: 10.12007/j.issn.0258-4646.2016.10.014

• 论著 • 上一篇    下一篇

瘘管性肛周脓肿细菌培养及药敏分析

张学诚 1,张力方 2,王书君 3   

  1. 1 承德医学院附属医院肛肠科,河北 承德 067000;2 承德市妇幼保健院妇科,河北 承德 067000;3 承德医学院附属医院骨伤科,河北 承德 067000
  • 收稿日期:2016-05-17 出版日期:2016-10-30 发布日期:2016-10-11
  • 作者简介:张学诚(1979 -),男,主治医师,硕士 .
  • 基金资助:
    承德市科技支撑计划项目(201422032)

Pathogen Distribution and Drug Sensitivity Analysis in Perianal Abscess Patients with Fistula

ZHANG Xuecheng1,ZHANG Lifang2,WANG Shujun3   

  1. 1 Anus-intestines Department,The Affiliated Hospital of Chengde Medical College,Chengde 067000,China;2 Department of Gynecology,Chengde Maternal and Child Health Care Hospital,Chengde 067000,China;3 Department of Orthopaedics and Traumatology,The Affiliated Hospital of Chengde Medical College
  • Received:2016-05-17 Online:2016-10-30 Published:2016-10-11

摘要: 目的 了解瘘管性肛周脓肿主要致病菌分布情况以及药物敏感情况,以指导临床合理使用抗生素。方法 回顾性分析瘘管性肛周脓肿患者 300 例,采集肛周脓液,进行细菌培养鉴定,并对培养菌进行药敏试验。结果 300 例患者中 277 例细菌培养阳性,阳性率为 92.3%,共培养分离出 369 株病原菌,革兰阳性菌 42 株(占 11.4%),革兰阴性菌 327 株(占 88.6%),其中大肠埃希菌 204 株(占 55.3%),其次为肺炎克雷伯菌 67 株(占 18.2%)。革兰阳性菌对利奈唑烷和万古霉素敏感性最好;革兰阴性菌对亚胺培南和哌拉西林敏感性较好,敏感性均在 95%以上。结论 瘘管性肛周脓肿以肠源性细菌感染为主要来源,革兰阳性菌应首选利奈唑烷和万古霉素进行治疗,革兰阴性菌应首选亚胺培南和哌拉西林进行治疗。

关键词: 瘘管性肛周脓肿, 细菌培养, 耐药性

Abstract: Objective To understand the main pathogenic bacteria distribution and drug sensitive situation in perianal abscess patients with fistula,so as to guide the rational use of antibiotics. Methods A total of 300 perianal abscess patients with fistula were retrospectively analyzed. Crissum pus was adopted for pus bacterial culture,identification and drug sensitive test. Results Among 300 patients,277 were positive for germicultured with the positive rate of 92.3%. A total of 369 isolated strains of pathogenic bacteria were successful obtained,including 42 strains(11.4%)of gram-positive bacteria and 327 strains(88.6%)of gram-negative bacteria,of which 204 strains(55.3%)were Escherichia coli,followed by 67 strains(18.2%)of Klebsiella pneumoniae. The best two antibiotics of gram-positive bacterium were linezolid and vancomycin. The best two antibiotics of gram-negative bacterium were imipenem and piperacillin. All of them had a sensitivity above 95%. Conclusion Enterogenous infection was the main source of perianal abscess with fistula. The linezolid and vancomycin should be preferred for gram-positive bacteria treatment,and imipenem and piperacillin should be preferred for bacterium of gram-negative treatment.

Key words: perianal abscess with fistula, bacterial culture, drug resistance

中图分类号: 

  • R657.1
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