中国医科大学学报

中国医科大学学报
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中国医科大学学报 ›› 2017, Vol. 46 ›› Issue (3): 219-222.doi: 10.12007/j.issn.0258-4646.2017.03.007

• 论著 • 上一篇    下一篇

不完全川崎病患儿的实验室检查分析

朱迪,罗钢   

  1. 中国医科大学附属第一医院儿科,沈阳 110001
  • 收稿日期:2016-10-25 出版日期:2017-03-30 发布日期:2017-01-20
  • 通讯作者: 罗钢 E-mail:syluogang@sina.com
  • 作者简介:朱迪(1989 -),男,助教,硕士 .
  • 基金资助:
    辽宁省自然科学基金(2015020534)

Analysis of the Laboratory Examination of Children with Incomplete Kawasaki Disease

ZHU Di,LUO Gang   

  1. Department of Pediatrics,The First Hospital,China Medical University,Shenyang 110001,China
  • Received:2016-10-25 Online:2017-03-30 Published:2017-01-20

摘要: 目的 总结并探讨近 10 年来不完全川崎病(IKD)患儿的实验室指标特点,为 IKD 早期诊断提供一定的依据。方法 对2005 至 2015 年间在中国医科大学附属第一医院住院的 67 例 IKD 患儿和随机选择的同期 67 例呼吸道感染(细菌感染)住院患儿的实验室指标进行回顾性分析。结果 IKD 患儿年龄为 2 个月~11 岁 4 个月,平均年龄 31 个月,86.5%的患儿<5 岁,男女比例约为 2∶1,春夏季发病占 72%;实验室指标中白细胞、C 反应蛋白、谷丙转氨酶、谷草转氨酶、谷氨酰转肽酶、血小板升高以及血红蛋白、血清白蛋白降低的发生率分别为 82%、94%、27%、24%、45%、72%、61%、94%。结论 血红蛋白<109 g/L、血清白蛋白<34 g/L、血小板>393×109/L、C 反应蛋白>74 mg/L、谷丙转氨酶>51 U/L、谷氨酰转肽酶>43 U/L 对 IKD 的早期诊断可能具有一定的参考价值。

关键词: 不完全川崎病, 实验室指标, 早期诊断

Abstract: Objective To summarize and discuss the laboratory characteristics of children with incomplete Kawasaki disease(IKD)in recent 10 years and provide some evidence for early diagnosis. Methods A retrospective review was performed on 67 children with IKD and 67 children with respiratory tract infection(bacterial infection)from 2005 to 2015 in the First Hospital of China Medical University. Results The age of children with IKD varied from 2 months to 11.3 years,with the average age of 31 months. Totally 86.5% of the children were less than 5 years old. The male to female ratio was 2∶1. The incidence of the disease in spring and summer was 72%. The incidences of the increasing of white blood cell,C- reactive protein,alanine aminotransferase,aspartate aminotransferase,glutamyl transpeptidase,and platelet and the decreasing of hemoglobin and serum albumin were 82%,94%,27%,24%,45%,72%,61%,and 94%,respectively. Conclusion The levels of the hemoglobin(<109 g/L), serum albumin(<34 g/L),platelet(>393×109/L),C-reactive protein(>74 mg/L),alanine aminotransferase(>51 U/L),and glutamyl transpeptidase(>43 U/L)may have a certain reference value for the early diagnosis of IKD.

Key words: incomplete Kawasaki disease, laboratory parameter, early diagnosis

中图分类号: 

  • R725.4
[1] 刘铮,张海英. 神经系统症状为突出表现的13例血栓性血小板减少性紫癜早期诊断分析[J]. 中国医科大学学报, 2014, 43(8): 756-759.
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