中国医科大学学报

中国医科大学学报
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中国医科大学学报 ›› 2017, Vol. 46 ›› Issue (3): 251-254.doi: 10.12007/j.issn.0258-4646.2017.03.015

• 论著 • 上一篇    下一篇

脂代谢紊乱患者牙种植体稳定性的评价

石莹,姬晓炜,李晶,姚源,单健良,何惠宇   

  1. 新疆医科大学附属第一医院口腔修复科,乌鲁木齐 830054
  • 收稿日期:2016-08-18 出版日期:2017-03-30 发布日期:2017-01-20
  • 通讯作者: 何惠宇 E-mail:hehuiyu01@126.com
  • 作者简介:石莹(1988 -),女,硕士研究生 .
  • 基金资助:
    新疆乌鲁木齐市科技局科学技术计划(Y151310006)

Evaluation of Dental Implants Stability in Patients with Lipid Metabolism Disorder

SHI Ying,JI Xiaowei,LI Jing,YAO Yuan,SHAN Jianliang,HE Huiyu   

  1. Department of Oral Rehabilitation,The First Affiliated Hospital,Xinjiang Medical University,Urumqi 830054,China
  • Received:2016-08-18 Online:2017-03-30 Published:2017-01-20

摘要: 目的 研究脂代谢紊乱的牙列缺损患者种植义齿修复后唾液中炎性细胞因子表达和种植体稳定性,分析脂代谢紊乱患 者的种植预后状况。方法 将脂代谢紊乱的牙列缺损患者设为实验组,血脂健康的牙列缺损患者设为对照组,在种植前,种植 后 1 个月、3 个月收集患者唾液,ELISA 方法检测唾液中的白细胞介素 6(IL-6)、白细胞介素 1β(IL-1β)、肿瘤坏死因子 α(TNF-α) 表达,Osstell ISQTM 共振频率无线分析仪检测种植体的稳定性,并用 Florida 探针检测牙周状况。结果 2 组种植后探诊深度(PD)、出血指数(BI)、共振频率无线分析仪检测种植体稳定系数(ISQ)无统计学差异(均 P > 0.05)。2 组种植前,种植后 1 个月、3 个月 ISQ 值,IL-6、IL-1β、TNF-α 表达比较差异有统计学意义(均 P < 0.05)。种植前实验组 IL-6、IL-1β、TNF-α 的表达高于对照组(均 P < 0.05);而实验组种植后 3 个月与对照组种植前 IL-6、IL-1β、TNF-α 的表达均无统计学差异(均 P > 0.05)。结论 种植术后脂代谢紊乱患者同血脂健康者一样具有良好的种植体稳定性,即脂代谢紊乱患者同样可以取得良好的种植预后。

关键词: 脂代谢紊乱, 种植体, 非刺激性全唾液, 共振频率分析

Abstract: Objective To study the expression of inflammatory factors in the saliva and the stability of implants after implant denture repair in patients with dysplasia of the dentition defect,and to analyze the prognosis of patients with lipid metabolic disorder. Methods The dentition defect patients with lipid metabolism disorder were selected as the experimental group. Patients with lipid defect were selected as the control group. Saliva was collected before implantation,1 month and 3 months after implantation. ELISA method was used to detect IL- 6,IL-1β and TNF- α. Osstell ISQTM radio frequency analyzer was used to detect the stability of the implants and the periodontal status was detected by Florida probe. Results There were no significant differences in the depth of implant probing(PD),bleeding index(BI)and ISQ between the two groups by radio frequency analyzer(all P > 0.05). The levels of IL-6,IL-1β and TNF-α in the pre-implantation,1 month and 3 months after implantation were sig- nificantly higher than those in the control group(all P < 0.05). The levels of IL-6,IL-1β and TNF-α in the experimental group were significantly higher than those in the control group before planting(all P < 0.05) 3 months after planting,there were no significant differences of IL-6,IL-1β,and TNF- α between the experimental group and control group(all P > 0.05). Conclusion The patients with dyslipidemia after implantation have good implant stability as those with normal blood lipid,and the patients with dyslipidemia can also obtain good prognosis.

Key words: disorder of lipid metabolism, implant, whole unstimulated saliva, resonance frequency analysis

中图分类号: 

  • R783.6
[1] 张楠楠,高妍. 微小种植体支抗手术的护理配合[J]. 中国医科大学学报, 2016, 45(4): 380-381.
[2] 宛莉娜,赵震锦,陈钰文,张扬,邢庆昱. 愈合时间对微螺钉种植体-骨结合方式的影响[J]. 中国医科大学学报, 2013, 42(5): 425-428.
[3] 易新, 马嘉, 张扬, 王强. 正畸不锈钢种植体的细胞毒性评价[J]. 中国医科大学学报, 2009, 38(12): 904-.
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