中国医科大学学报

中国医科大学学报
  • 中文核心期刊
  • 中国科技核心期刊
  • 中国高校百佳科技期刊
  • BA、CA收录

中国医科大学学报 ›› 2018, Vol. 47 ›› Issue (1): 58-61,66.doi: 10.12007/j.issn.0258-4646.2018.01.013

• 论著 • 上一篇    下一篇

不同性别代谢综合征患者腹内脂肪厚度与其他患病因素的关系

徐世燚, 王学梅, 张茜, 周冰冰   

  1. 中国医科大学附属第一医院超声科, 沈阳 110001
  • 收稿日期:2017-02-27 出版日期:2018-01-30 发布日期:2017-12-23
  • 通讯作者: 王学梅 E-mail:wxmlmt@163.com
  • 作者简介:徐世燚(1989-),女,硕士研究生.

Correlation between Intra-abdominal Fat Thickness and Components of Metabolic Syndrome with Regard to Gender Differences

XU Shiyi, WANG Xuemei, ZHANG Qian, ZHOU Bingbing   

  1. Department of Ultrasound, The First Hospital, China Medical University, Shenyang 110001, China
  • Received:2017-02-27 Online:2018-01-30 Published:2017-12-23

摘要: 目的 探讨不同性别代谢综合征(MS)患者患病情况,分析腹内脂肪厚度与MS及其患病因素的性别差异。方法 2015年5月采用横断面调查的方法调查沈阳市某居民区505例中老年人,其中男249例、女256例。根据2009年IDF AHA/NHLBI诊断标准诊断MS患者205例,其中男124例、女81例。检测MS患者各项指标,超声测量腹内脂肪厚度。结果 男性MS患病率高于女性(P < 0.01)。男性MS患者腰围、血糖异常发生率高于女性,而HDL-C异常发生率低于女性,差异均有统计学意义(均P < 0.05)。多因素logistic回归分析结果显示,调整其他因素后,腹内脂肪厚度是男性发生MS的独立危险因素(OR=1.304,95%CI:1.014~1.676,P=0.039),而不是女性发生MS的独立危险因素(OR=1.257,95%CI:0.984~1.605,P=0.067)。逐步多元线性回归结果显示腹内脂肪厚度在男性MS患者中与年龄、腰围、2 h INS呈线性相关;而在女性MS患者中仅与腰围呈线性相关。结论 男女MS患病率及MS诊断条件发生率均存在差异,腹内脂肪厚度是男性发生MS的独立危险因素。腹内脂肪在男性发生MS的作用不能简单地被腰围因素所替代。

关键词: 性别, 代谢综合征, 超声, 腹内脂肪

Abstract: Objective To investigate gender differences in the prevalence of metabolic syndrome (MS) and to explore the relationship between intra-abdominal fat thickness and MS and its components with respect to gender differences. Methods Based on gender and IDF AHA/NHLBI criteria used to diagnose MS,205 middle-aged and elderly urban residents were divided into a male MS group (124 patients) and a female MS group (81 patients). The relative indices and the thickness of intra-abdominal fat were measured. Results The prevalence of MS was observed to be higher in men (P < 0.01). A greater number of men than women showed waist circumference and blood glucose abnormalities,but fewer men than women showed high-density lipoprotein cholesterol (HDL-C) abnormalities (P < 0.05). Multivariate logistic regression analysis showed that after adjusting for potential confounding factors,intra-abdominal fat thickness was an independent predictor in men,but not in women (men:OR=1.304,95%CI:1.014-1.676,P=0.039,women:OR=1.257,95%CI:0.984-1.605,P=0.067). Intra-abdominal fat thickness was linearly correlated with age,waist circumference,and the 2-hour insulin levels in men,but only linearly correlated with waist circumference in women. Conclusion Prevalence of MS and MS components varies between genders. Intra-abdominal fat thickness was an independent predictor of MS in men. The role of intra-abdominal fat thickness as a determinant of MS in men can not be replaced by the waistline circumference alone as determined in women.

Key words: gender, metabolic syndrome, ultrasound, intra-abdominal fat thickness

中图分类号: 

  • R589
[1] ZHANG GM,ZHU Y,YE DW. Metabolic syndrome and renal cell carcinoma[J]. World J Surg Oncol,2014,12(1):236. DOI:10.1186/1477-7819-12-236.
[2] MONTELLA M,MASO MD,CRISPO A,et al. Metabolic syndrome and the risk of urothelial carcinoma of the bladder:a case-control study[J]. BMC Cancer,2015,15(1):720. DOI:10.1186/s12885-015-1769-9.
[3] POPA S,MOA M,POPA A,et al. Prevalence of overweight/obesity,abdominal obesity and metabolic syndrome and atypical cardiometabolic phenotypes in the adult Romanian population:PREDATORR study[J]. J Endocrinol Investigation,2016,39(9):1045-1053. DOI:10.1007/s40618-016-0470-4.
[4] XU S,GAO B,XING Y,et al. Gender differences in the prevalence and development of metabolic syndrome in chinese population with abdominal obesity[J]. PLos One,2013,8(10):e78270-e78270. DOI:10.1371/journal.pone.0078270.
[5] TURKER Y,BALTACI D,TURKER Y,et al. Investigation of relationship of visceral body fat and inflammatory markers with metabolic syndrome and its components among apparently healthy individuals[J]. Int J Clin Exp Med,2015,8(8):13067.
[6] DEMERATH EW,SUN SS,ROGERS N,et al. Anatomical patterning of visceral adipose tissue:race,sex,and age variation[J]. Obesity,2007,15(12):2984-2993. DOI:10.1038/oby.2007.356.
[7] XIAO J,WU CL,GAO YX,et al. Prevalence of metabolic syndrome and its risk factors among rural adults in Nantong,China[J]. Sci Reports,2016,6:38089. DOI:10.1038/srep38089.
[8] 徐少勇. 中国人群代谢综合征患病率及其相关问题的流行病学研究[D]. 西安:第四军医大学,2016.
[9] 马杰,杨明,韩凌,等. 北方秋冬季气温下降对高血压患者血压的影响[J].中华临床医师杂志(电子版),2015,9(4):559-562. DOI:10.3877/cma.j.issn.1674-0785.2015.04.010.
[10] MEDINAURRUTIA A. Role of adiponectin and free fatty acids on the association between abdominal visceral fat and insulin resistance[J]. Cardiovascular Diabetol,2015,14(1):20. DOI:10.1186/s12933-015-0184-5.
[11] HWANG YC,FUJIMOTO WY,HAYASHI T,et al. Increased visceral adipose tissue is an independent predictor for future development of atherogenic dyslipidemia[J]. J Clin Endocrinol Metabolism,2015,2015:3246. DOI:10.1210/jc.2015-3246.
[12] XIA MF,YING C,LIN HD,et al. An indicator of visceral adipose dysfunction to evaluate metabolic health in adult Chinese[J]. Sci Rep,2016,6:38214. DOI:10.1038/srep38214.
[13] 周寿,胡弼. 雌激素与胰岛素抵抗及代谢综合征的关系[J].国际内分泌代谢杂志,2005,25(3):198-200. DOI:10.3760/cma.j.issn.1673-4157.2005.03.024.
[14] BRAND J,VAN DER TWEEL I,GROBBEE D,et al. Testosterone,sex hormone binding globulin and the metabolic syndrome:a systematic review and meta-analysis of observational studies[J]. Int J Epidemiol,2011,40(1):189-207. DOI:10.1093/ije/dyq158.
[15] 赵文燕,董耀,仇树林.脂肪细胞雌激素受体的表达及其与人体脂肪分布的相关性[J]. 中国美容医学杂志,2005,14(5):534-536. DOI:10.3969/j.issn.1008-6455.2005.05.005.
[1] 庄连婷, 黄瑛. 靶向纳米粒超声造影剂的研究进展[J]. 中国医科大学学报, 2018, 47(9): 842-846.
[2] 秦丽梅, 吴琳, 吴镇先. 不同强度超声波对多孔钛合金支架上成骨细胞生物学行为的影响[J]. 中国医科大学学报, 2018, 47(8): 708-712.
[3] 杨焕, 任卫东. 心内膜弹力纤维增生症的超声诊断及研究进展[J]. 中国医科大学学报, 2018, 47(8): 735-739.
[4] 赵梦楠, 张义侠, 刘妍, 宋涛. 超声引导下注射治疗肱二头肌长头腱炎的疗效分析[J]. 中国医科大学学报, 2018, 47(8): 750-752.
[5] 范苗, 任卫东, 宋光, 李颖. 三维径向应变评价射血分数保留的心力衰竭患者左心室收缩功能变化[J]. 中国医科大学学报, 2018, 47(7): 581-584.
[6] 丁颖, 刘洁. 超声诊断急性胰腺炎累及肾周间隙积液的临床价值[J]. 中国医科大学学报, 2018, 47(7): 655-657.
[7] 肖甄男, 商丽华, 龙波. 超声引导腹横肌平面阻滞复合右美托咪定在老年患者腹股沟疝修补术术中及术后的镇痛效果[J]. 中国医科大学学报, 2018, 47(6): 507-512.
[8] 周巧兰, 于丽杰. 妊娠中晚期胎儿肺动脉超声参数分析[J]. 中国医科大学学报, 2018, 47(5): 411-414.
[9] 张倩, 李芷舒, 张宇明, 王英华, 白璐, 鲁海鸥, 于月新. 反复移植失败患者子宫内膜容受性的超声评价[J]. 中国医科大学学报, 2018, 47(4): 350-354.
[10] 赵梦峤, 任卫东, 胡金玲. 7例主肺间隔缺损患者超声特征分析[J]. 中国医科大学学报, 2018, 47(2): 171-174.
[11] 鞠浩, 李士星, 时博, 刘博威, 王烁, 侯成, 石锋. 23例Ⅰ型阴道斜隔患者的超声图像特点分析[J]. 中国医科大学学报, 2018, 47(12): 1146-1149.
[12] 李宇, 马虹. 超声引导星状神经节阻滞对患者全身麻醉期间血流动力学的影响[J]. 中国医科大学学报, 2018, 47(12): 1093-1097.
[13] 王笑楠, 汪旭, 孙明军, 王颖, 刘梦园, 宋顺喆, 李妍霞, 褚旭芳. 超声内镜诊断肠道子宫内膜异位症的临床价值[J]. 中国医科大学学报, 2018, 47(11): 1036-1038.
[14] 王佳莉,任卫东,王欣,赵梦峤. 超声动脉分析技术评价妊娠期高血压患者的颈动脉 径向应变和应变率[J]. 中国医科大学学报, 2017, 46(8): 686-688.
[15] 杨卓 ,杨飞 ,陈英汉 ,李妍 ,刘岿然 ,欧阳玲. 直肠超声内镜在直肠阴道膈子宫内膜异位症诊断中的应用[J]. 中国医科大学学报, 2017, 46(8): 689-693.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!

中国医科大学学报版权所有©2018

未经允许,严禁擅自转载本站图文资料

地址:中国 沈阳市沈北新区蒲河路77号 110122

辽ICP备05014850

JOURNAL OF CHINA MEDICAL UNIVERSITY

ADDRESS: NO.77 PUHE ROAD

SHENYANG NORTH NEW AREA, SHENYANG

LIAONING PROVINCE, P.R. CHINA