中国医科大学学报

中国医科大学学报
  • 中文核心期刊
  • 中国科技核心期刊
  • 中国高校百佳科技期刊
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中国医科大学学报 ›› 2018, Vol. 47 ›› Issue (3): 256-259.doi: 10.12007/j.issn.0258-4646.2018.03.015

• 论著 • 上一篇    下一篇

脑出血后神经源性肺水肿的相关因素分析

杜绍楠, 刘志   

  1. 中国医科大学附属第一医院急诊科, 沈阳 110001
  • 收稿日期:2017-09-05 出版日期:2018-03-30 发布日期:2018-03-24
  • 通讯作者: 刘志 E-mail:liuzhicmu@163.com
  • 作者简介:杜绍楠(1988-),男,医师,硕士.
  • 基金资助:
    沈阳市科学技术计划(F16-206-9-02)

Analysis of Factors Associated with Neurogenic Pulmonary Edema after Intracerebral Hemorrhage

DU Shaonan, LIU Zhi   

  1. Department of Emergency, The First Hospital, China Medical University, Shenyang 110001, China
  • Received:2017-09-05 Online:2018-03-30 Published:2018-03-24

摘要: 目的 分析脑出血后神经源性肺水肿(NPE)患者的各项临床指标,探讨NPE的相关因素。方法 收集2014年5月至2017年5月我院急诊科收治的116例脑出血患者的临床资料,分为NPE组和非NPE组,比较2组各项指标,通过logistic回归分析NPE发生的相关因素。结果 氧合指数、乳酸浓度、pH、PCO2、血清脑钠素(BNP)、格拉斯哥昏迷评分(GCS) 2组比较差异均有统计学意义(均P < 0.05)。logistic多变量回归分析显示,氧合指数(B=0.049;OR=1.05;P=0.04)和乳酸水平(B=-5.855;OR=0.003;P=0.01)与脑出血后NPE相关。结论 脑出血患者氧合指数降低和血清乳酸水平增加与脑出血后NPE相关,可作为该病早期诊断的指标。

关键词: 脑出血, 神经源性肺水肿, 氧合指数, 乳酸水平, 相关分析

Abstract: Objective To determine the association of the oxygenation index and lactate levels with neurogenic pulmonary edema (NPE) in patients with intracerebral hemorrhage. Methods We retrospectively evaluated 116 patients with intracerebral hemorrhage,who were admitted to the First Affiliated Hospital of China Medical University between May 2014 and May 2017. Patients were divided into NPE and non-NPE groups and the groups were compared to identify the factors associated with the occurrence of NPE. Results The oxygenation index,lactate level,pH,PCO2,brain natriuretic peptide (BNP) level,and Glasgow coma scale were significantly different between the NPE and non-NPE groups (all P < 0.05). Logistic regression analysis showed that the oxygenation index (B=0.049;OR=1.05;P=0.04) and lactic acid level (B=-5.855;OR=0.003;P=0.01) were associated with the occurrence of NPE in patients with intracerebral hemorrhage. Conclusion A decrease in oxygenation index and an increase in serum lactate level are directly associated with the occurrence of NPE in patients with intracerebral hemorrhage.

Key words: intracerebral hemorrhage, neurogenic pulmonary edema, oxygenation index, lactic, correlation analysis

中图分类号: 

  • R743.3
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