中国医科大学学报

中国医科大学学报
  • 中文核心期刊
  • 中国科技核心期刊
  • 中国高校百佳科技期刊
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中国医科大学学报 ›› 2018, Vol. 47 ›› Issue (12): 1116-1118,1132.doi: 10.12007/j.issn.0258-4646.2018.12.014

• 论著 • 上一篇    下一篇

子宫内膜病变筛查中负压型子宫内膜取样器的应用价值

李丰鑫1, 窦磊1, 田东立1, 吴广平2, 庞晓燕1, 张颐1   

  1. 1. 中国医科大学附属第一医院妇科, 沈阳 110001;
    2. 中国医科大学附属第一医院病理科, 沈阳 110001
  • 收稿日期:2018-07-18 出版日期:2018-12-06 发布日期:2018-12-06
  • 通讯作者: 张颐 E-mail:syzi@163.com
  • 作者简介:李丰鑫(1993-),女,硕士研究生.
  • 基金资助:
    沈阳市科技计划(17-231-1-54)

Application Value of Negative Pressure Endometrial Sampler in Screening Endometrial Lesions

LI Fengxin1, DOU Lei1, TIAN Dongli1, WU Guangping2, PANG Xiaoyan1, ZHANG Yi1   

  1. 1. Department of Gynecology, The First Hospital, China Medical University, Shenyang 110001, China;
    2. Department of Pathology, The First Hospital, China Medical University, Shenyang 110001, China
  • Received:2018-07-18 Online:2018-12-06 Published:2018-12-06

摘要: 目的 探讨负压型子宫内膜取样器获取子宫内膜细胞学诊断和组织病理学诊断的准确性、组织样本的质量及在子宫内膜病变早期诊断中的临床应用价值。方法 选择2017年6月至9月于中国医科大学附属第一医院行宫腔镜手术的患者95例,首先使用一次性负压型子宫内膜取样器进行子宫内膜取样,分别进行细胞学及病理学检查,再由同一操作者进行宫腔镜检查或治疗,记录并比较2种方法的安全性、标本满意度及病理的符合率(子宫内膜细胞学检查及组织病理学检查)。结果 负压型子宫内膜取样器在细胞学及组织学标本检查中,二者联合取材的标本满意率为96.84%,宫腔镜标本取材的标本满意率为100.00%,差异无统计学意义(P > 0.05)。以宫腔镜结果为金标准,负压型子宫内膜取样器行细胞学检查的灵敏度为77.78%,特异度为92.21%,符合率为89.47%;负压型子宫内膜取样器行组织病理学检查的灵敏度为77.78%,特异度为98.70%,符合率为94.74%;细胞学及组织学标本二者联合诊断的灵敏度为100.00%,特异度为90.91%,符合率为92.63%。所有患者无大量出血、穿孔、宫颈裂伤等并发症。结论 负压型子宫内膜取样器可用于子宫内膜病变的早期筛查,操作简单、安全性好,细胞学及组织学联合诊断子宫内膜病变具有较高的准确性和安全性。

关键词: 子宫内膜病变, 负压型子宫内膜取样器, 宫腔镜检查, 筛查

Abstract: Objective To evaluate the accuracy of endometrial cytological and histopathological diagnosis,the quality of tissue samples,and the clinical value in the early diagnosis of endometrial lesions using negative pressure endometrial sampler. Methods A total of 95 patients undergoing hysteroscopic surgery from June to September 2017 at The First Hospital,China Medical University,were selected. First,a disposable negative pressure endometrial sampler was used to obtain samples for cytological and histopathological examination. Then,hysteroscopy was performed by the same operator. The safety and satisfaction rate of specimens and the consistency of the pathology (cytological and histopathological examination) were recorded and compared. Results The satisfaction rates of specimens obtained from the negative pressure endometrial sampler in combined cytology and histology and hysteroscopy were 96.84% and 100.00%,respectively,without statistical difference (P > 0.05). Using hysteroscopic results as the gold standard,the sensitivity,specificity,and coincidence rate of the negative pressure endometrial sampler for cytological examination were 77.78%,92.21%,and 89.47%,respectively,whereas those for the histopathological examination were 77.78%,98.70%,and 94.74%,respectively. The sensitivity,specificity,and coincidence rate of the combined diagnosis were 100.00%,90.91%,and 92.63%,respectively. Hemorrhage,perforation,cervical laceration,and other complications were not observed. Conclusion The negative pressure endometrial samplers can be used for early screening of endometrial lesions and is a simple and safe operation. The combined cytological and histological diagnosis of endometrial lesions is highly accurate and safe.

Key words: endometrial lesions, negative pressure endometrial sampler, hysteroscopy, screening

中图分类号: 

  • R711.32
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