中国医科大学学报

中国医科大学学报
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  • 中国科技核心期刊
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中国医科大学学报 ›› 2019, Vol. 48 ›› Issue (6): 507-510.doi: 10.12007/j.issn.0258-4646.2019.06.007

• 论著 • 上一篇    下一篇

老年无骨折脱位颈脊髓损伤患者术后谵妄相关危险因素分析

宇洪浩, 原泉   

  1. 中国医科大学附属盛京医院脊柱外科, 沈阳 110004
  • 收稿日期:2019-02-26 出版日期:2019-06-30 发布日期:2019-05-29
  • 通讯作者: 原泉 E-mail:spring@sj-hospital.org
  • 作者简介:宇洪浩(1985-),男,医师,硕士.
  • 基金资助:
    辽宁省自然科学基金(20180530088)

Risk Factors Associated with Postoperative Delirium in Elderly Patients with Cervical Spinal Cord Injury without Fracture and Dislocation

YU Honghao, YUAN Quan   

  1. Spinal Surgery Ward, Shengjing Hospital, China Medical University, Shenyang 110004, China
  • Received:2019-02-26 Online:2019-06-30 Published:2019-05-29

摘要: 目的 探讨老年无骨折脱位的颈脊髓损伤(CSCIWFD)后路单开门微型钢板内固定患者术后谵妄的发生率及其相关危险因素。方法 回顾分析2015年10月至2018年1月于我院接受颈椎后路单开门微型钢板内固定治疗的65岁以上CSCIWFD患者304例,利用患者人口学、实验室和手术相关信息,计算CSCIWFD后路术后谵妄发病率。应用logistic逐步回归分析,筛选出老年CSCIWFD术后谵妄的独立危险因素。结果 304例患者中有48例(15.79%)发生术后谵妄,年龄65~88岁,平均74.5岁。发生时间为手术当天至手术后3 d之间,平均为1.2 d。谵妄的持续时间为1~8 d,平均为3.1 d。应用logistic逐步回归分析,结果显示酗酒史、糖尿病、术后低血红蛋白和脑脊液漏是老年CSCIWFD术后谵妄发生的独立危险因素。结论 酗酒史、糖尿病、术后低血红蛋白和脑脊液漏是老年CSCIWFD后路术后谵妄发生的独立危险因素。

关键词: 颈脊髓损伤, 谵妄, 危险因素

Abstract: Objective To investigate the incidence and risk factors of delirium in elderly patients with cervical spinal cord injury without fracture and dislocation (CSCIWFD) after posterior single-door miniplate internal fixation. Methods From October 2015 to January 2018,304 patients with CSCIWFD aged over 65 years who underwent posterior cervical single-door mini-plate internal fixation were retrospectively analyzed. The incidence of delirium after CSCIWFD was calculated using demographic,laboratory,and surgical information. Multivariate stepwise logistic regression analysis was used to screen independent risk factors for delirium in elderly patients after CSCIWFD. Results Among 304 patients,48 (15.79%) had postoperative delirium;the average age of these patients was 74.5 (range,65-88) years. Delirium was observed between the day of operation and 3 days after operation,with an average of 1.2 days. The duration of delirium ranged from 1 to 8 days,with an average of 3.1 days. Logistic stepwise regression analysis showed that alcohol abuse,diabetes mellitus,postoperative low hemoglobin level,and cerebrospinal fluid leakage were independent risk factors for delirium after CSCIWFD in elderly patients. Conclusion Alcoholism,diabetes mellitus,postoperative low hemoglobin level,and cerebrospinal fluid leakage are independent risk factors for delirium after CSCIWFD in elderly patients.

Key words: cervical spinal cord injury, delirium, risk factor

中图分类号: 

  • R749.1
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