中国医科大学学报

中国医科大学学报
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中国医科大学学报 ›› 2019, Vol. 48 ›› Issue (6): 519-524.doi: 10.12007/j.issn.0258-4646.2019.06.010

• 论著 • 上一篇    下一篇

急性冠状动脉综合征患者经皮冠状动脉介入治疗术后谵妄的回顾性分析

范蒙蒙1, 马晶茹2   

  1. 1. 沈阳医学院研究生院, 沈阳 110034;
    2. 沈阳医学院附属第二医院心血管内科, 沈阳 110035
  • 收稿日期:2018-09-18 出版日期:2019-06-30 发布日期:2019-05-29
  • 通讯作者: 马晶茹 E-mail:majingru1218@163.com
  • 作者简介:范蒙蒙(1992-),女,医师,硕士.
  • 基金资助:
    辽宁省重点研发计划指导项目(2018225063)

Retrospective Analysis of Delirium after Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome

FAN Mengmeng1, MA Jingru2   

  1. 1. Graduate School of Shenyang Medical College, Shenyang 110034, China;
    2. Department of Cardiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110035, China
  • Received:2018-09-18 Online:2019-06-30 Published:2019-05-29

摘要: 目的 探讨急性冠状动脉综合征(ACS)患者经皮冠状动脉介入治疗(PCI)术后出现谵妄的发生率及相关危险因素。方法 回顾性分析2013年4月至2017年4月沈阳医学院附属第二医院心血管内科PCI术后878例ACS患者的相关资料,按有无谵妄分为2组,采用单因素和二元logistic回归分析研究ACS患者PCI术后谵妄的独立危险因素。结果 878例患者中,谵妄组15例(1.71%),对照组863例(98.29%)。单因素分析显示,谵妄组与对照组患者的年龄、睡眠障碍、肾小球滤过率(eGFR)、冠状动脉病变程度具有统计学差异;将单因素分析具有统计学差异的自变量代入二元logistic回归分析模型,结果显示年龄、睡眠障碍、冠状动脉病变程度具有统计学差异。结论 年龄、睡眠障碍、冠状动脉病变程度为ACS患者PCI术后谵妄的独立危险因素。

关键词: 急性冠状动脉综合征, 经皮冠状动脉介入治疗, 谵妄

Abstract: Objective To investigate the incidence and risk factors for delirium after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). Methods We retrospectively analyzed the relevant data of 878 patients with ACS who underwent PCI in the department of cardiovascular medicine of the second affiliated hospital of Shenyang Medical College from April 2013 to April 2017. The patients were divided into 2 groups based on the occurrence of delirium,and independent risk factors for secondary delirium in these patients were analyzed using univariate and binary logistic regression. Results Of the 878 patients enrolled in the study,15 (1.71%) belonged to the delirium group and 863 (98.29%) to the control group. Univariate analysis showed that age,sleep disorder occurrence,glomerular filtration rate,and severity of coronary artery disease differed significantly between the delirium and control groups. On incorporation of univariate analysis-derived statistical differences into the binary logistic regression,age,sleep disorder occurrence,and severity of coronary artery disease were found to be statistically different between the two groups. Conclusion Age,sleep disturbance,and severity of coronary artery disease are independent risk factors for delirium after PCI in patients with ACS.

Key words: acute coronary syndrome, percutaneous coronary intervention, delirium

中图分类号: 

  • R541.4
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