中国医科大学学报

中国医科大学学报
  • 中文核心期刊
  • 中国科技核心期刊
  • 中国高校百佳科技期刊
  • BA、CA收录

中国医科大学学报 ›› 2019, Vol. 48 ›› Issue (7): 633-637.doi: 10.12007/j.issn.0258-4646.2019.07.013

• 论著 • 上一篇    下一篇

气管-支气管结核患者焦虑和抑郁的现状及其影响因素

付颖辉1,2, 张庆3, 杨雪2, 侯刚1   

  1. 1. 中国医科大学附属第一医院呼吸和危重症医学科, 沈阳 110001;
    2. 沈阳市胸科医院结核科, 沈阳 110034;
    3. 沈阳市胸科医院内窥镜中心, 沈阳 110034
  • 收稿日期:2018-06-23 出版日期:2019-07-30 发布日期:2019-07-17
  • 通讯作者: 侯刚 E-mail:hou_gang@163.com
  • 作者简介:付颖辉(1982-),女,主治医师,本科.
  • 基金资助:
    辽宁省高等学校创新团队项目(LT2013015)

Prevalence and Influencing Factors for Anxiety and Depression in Patients with Tracheobronchial Tuberculosis

FU Yinghui1,2, ZHANG Qing3, YANG Xue2, HOU Gang1   

  1. 1. Department of Respiratory and Critical Medicine, The First Hospital, China Medical University, Shenyang 110001, China;
    2. Department of Tuberculosis, Shenyang Thoracic Hospital, Shenyang 110034, China;
    3. Endoscopic Centre, Shenyang Thoracic Hospital, Shenyang 110034, China
  • Received:2018-06-23 Online:2019-07-30 Published:2019-07-17

摘要: 目的 探讨气管-支气管结核(TBTB)患者焦虑和抑郁的现状及相关影响因素。方法 采用结构式问卷对辽宁省3家医院TBTB患者进行横断面调查。通过医院焦虑抑郁量表(HADS)评估患者抑郁和焦虑的情况。结果 336例TBTB患者中18.15%有抑郁症状,19.05%有焦虑症状。呼吸困难评分增加是抑郁症状的危险因素;呼吸困难评分增加和临床症状4种及以上是焦虑症状的危险因素(均P<0.05)。结论 TBTB患者常见抑郁症状和焦虑症状;呼吸困难评分增加及临床症状4种及以上是抑郁症状和焦虑症状的危险因素;筛查具有这些危险因素的TBTB患者至关重要。

关键词: 气管-支气管结核, 抑郁, 焦虑, 危险因素

Abstract: Objective To determine the prevalence and the associated risk factors for anxiety and depression in patients with tracheobronchial tuberculosis(TBTB). Methods A cross-sectional survey was performed among patients with TBTB in three hospitals in Liaoning Province using a structured questionnaire. The patients were assessed for depression and anxiety using the Hospital Anxiety and Depression Scale(HADS). Results According to the HADS results,of the surveyed 336 patients with TBTB,18.15% were diagnosed with depression and 19.05% were diagnosed with anxiety. High dyspnea score was the risk factor related to depression,whereas anxiety-related risk factors included high dyspnea score and clinical symptoms lasting ≥ 4(P<0.05 for all). Conclusion Patients with TBTB commonly develop depression and/or anxiety disorders,with the related high-risk factors being high dyspnea score and clinical symptoms lasting ≥ 4. Screening for depression and anxiety in these patients is critical for identifying those who need further psychological assessment and support.

Key words: tracheal-bronchial tuberculosis, depression, anxiety, risk factors

中图分类号: 

  • R765.2
[1] DUKO B,GEBEYEHU A,AYANO G. Prevalence and correlates of depression and anxiety among patients with tuberculosis at Wolaita Sodo University Hospital and Sodo Health Center,Wolaita Sodo, South Ethiopia,cross sectional study[J]. BMC Psychiatry,2015,14(15):214-220. DOI:10.1186/s12888-015-0598-3.
[2] H FNER K,FUCHS D,BLAUTH M,et al. How acute and chronic physical disease may influence mental health-an analysis of neurotransmitter precursor amino acid levels[J]. Psychoneuroendocrinology,2019,106:95-101. DOI:10.1016/j.psyneuen.2019.03.028.
[3] CHIREH B,LI M,D'ARCY C. Diabetes increases the risk of depression:a systematic review,meta-analysis and estimates of population attributable fractions based on prospective studies[J]. Prev Med Rep, 2019,14:100822. DOI:10.1016/j.pmedr.2019.100822.
[4] RAMANUJ P,FERENCHICK EK,PINCUS HA. Depression in primary care:part 2-management[J]. BMJ,2019,365:l835. DOI:10.1136/bmj.l835.
[5] VAN DAMME A,DECLERCQ T,LEMEY L,et al. Late-life depression:issues for the general practitioner[J]. Int J Gen Med,2018,11:113-120. DOI:10.2147/IJGM.S154876.
[6] KATON WJ. Epidemiology and treatment of depression in patients with chronic medical illness[J]. Dialog Clin Neurosci,2011,13(1):7-23.
[7] GALHENAGE JS,RUPASINGHE JP,ABEYWARDENA GS,et al. Psychological morbidity and illness perception among patients receiving treatment for tuberculosis in a tertiary care centre in Sri Lanka[J]. Ceylon Med J,2016,61(1):37-40. DOI:10.4038/cmj.v61i1.8261.
[8] TOLA HH,SHOJAEIZADEH D,GARMAROUDI G,et al. Psychological distress and its effect on tuberculosis treatment outcomes in Ethiopia[J]. Glob Health Action,2015,8:29019-29029. DOI:10.3402/gha.v8.29019.
[9] IGE OM,LASEBIKAN VO. Prevalence of depression in tuberculosis patients in comparison with non-tuberculosis family contacts visiting the DOTS clinic in a Nigerian tertiary care hospital and its correlation with disease pattern[J]. Ment Health Fam Med,2011,8(4):235-241.
[10] SIOW WT,LEE P. Tracheobronchial tuberculosis:a clinical review[J]. J Thorac Dis,2017,9(1):E71-E77. DOI:10.21037/jtd.2017.01.49.
[11] REDA AA. Reliability and validity of the Ethiopian version of the hospital anxiety and depression scale(HADS)in HIV infected patients[J]. PLoS One,2011,6(1):e16049-e16054. DOI:10.1371/journal.pone.0016049.
[12] BESTALL JC,PAUL EA,GARROD R,et al. Usefulness of the Medical Research Council(MRC)dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease[J]. Thorax,1999,54(7):581-586. DOI:10.1136/thx.54.7.581.
[13] UGARTE-GIL C,RUIZ P,ZAMUDIO C,et al. Association of major depressive episode with negative outcomes of tuberculosis treatment[J]. PLoS One,2013,8(7):e69514. DOI:10.1371/journal. pone.0069514.
[14] WANG XB,LI XL,ZHANG Q,et al. A survey of anxiety and depressive symptoms in pulmonary tuberculosis patients with and without tracheobronchial tuberculosis[J]. Front Psychiatry,2018,9:308-317. DOI:10.3389/fpsyt.2018.00308.
[15] ISSA BA,YUSSUF AD,KURANGA SI. Depression comorbidity among patients with tuberculosis in a university teaching hospital outpatient clinic in Nigeria[J]. Menta Health Fam Med,2009,6(3):133-138.
[16] MASUMOTO S,YAMAMOTO T,OHKADO A,et al. Prevalence and associated factors of depressive state among pulmonary tuberculosis patients in Manila,The Philippines[J]. Int J Tuberc Lung Dis, 2014,18(2):174-179. DOI:10.5588/ijtld.13.0335.
[17] CARTER GC,CANTRELL RA,VICTORIA Z,et al. Comprehensive review of factors implicated in the heterogeneity of response in depression[J]. Depress Anxiety,2012,29(4):340-354. DOI:10.1002/da.21918.
[18] MARTINEZ R,COSTAN G,ALCAZAR N,et al. Factors associated with depression in COPD:a multicenter study[J]. Lung,2016,194(3):335-343. DOI:10.1007/s00408-016-9862-7.
[19] MOUSSAS G,TSELEBIS A,KARKANIAS A,et al. A comparative study of anxiety and depression in patients with bronchial asthma, chronic obstructive pulmonary disease and tuberculosis in a general hospital of chest diseases[J]. Ann Gen Psychiatry,2008,7(1):7-10. DOI:10.1186/1744-859X-7-7.
[20] B EN H,DALGARD O,JOHANSEN R,et al. Socio-demographic, psychosocial and health characteristics of Norwegian senior centre users:a cross-sectional study[J]. Scand J Public Health,2010,38(5):508-517. DOI:10.1177/1403494810370230.
[21] FLUHARTY M,TAYLOR AE,GRABSKI M,et al. The association of cigarette smoking with depression and anxiety:a systematic review[J]. Nicotine Tob Res,2017,19(1):3-13. DOI:10.1093/ntr/ntw140.
[22] ECONOMOU M,MADIANOS M,PEPPOU LE,et al. Major depression in the era of economic crisis:a replication of a cross-sectional study across Greece[J]. J Affect Disord,2013,145(3):308-314. DOI:10.1016/j.jad.2012.08.008.
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