中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2009, Vol. 38 ›› Issue (10): 773–.

• 临床医学 • 上一篇    下一篇

绝经后妇女绒毛膜癌的临床分析

庞晓燕; 张颐   

  1. 中国医科大学附属第一医院妇科
  • 出版日期:2009-10-20 发布日期:2010-04-02
  • 通讯作者: 张颐 E-mail:syzi@163.com

Clinical Characteristics and Management of Choriocarcinoma in Postmenopausal Women

  • Online:2009-10-20 Published:2010-04-02

摘要:

目的探讨绝经后妇女绒毛膜癌的临床特点及治疗转归。方法回顾性分析134例妊娠滋养细胞肿瘤中6例绝经后妇女绒毛膜癌患者的治疗过程及结果。结果绝经后绒毛膜癌患者的主要临床表现为绝经后阴道流血。6例患者均接受了化疗,其中4例行全子宫及双附件切除术。6例绒毛膜癌患者中,3例完全缓解,1例部分缓解,1例病情稳定,1例疾病进展。随访后1例死亡,2例失访,3例存活至今。结论绝经后阴道流血的患者应考虑妊娠滋养细胞肿瘤的可能。确诊后,应及早给予化疗,化疗后手术切除全子宫及双附件可以取得相对满意的治疗效果。

关键词: 绝经后妇女, 绒毛膜癌, 妊娠滋养细胞肿瘤

Abstract:

Objective To investigate the clinical characteristics,management
      and prognosis of choriocarcinoma in postmenopausal women. Methods Six
      cases of choriocarcinoma in postmenopausal women were reviewed
      retrospectively. Results Four cases in the 6 patients presented with
      abnormal vaginal bleeding. All of the six cases received chemotherapy and
      four cases underwent hysterectomy. Three cases achieved complete
      remission,one partial remission,one stable condition,and one disease
      progression.One case died,two cases lost follow-up and three cases
      survived as follow-up so far. Conclusion The diagnosis of
      pregnancy-related disease should be considered in the elderly women
      presenting with abnormal vaginal bleeding.Once diagnosed,chemotherapy
      should be given as soon as possible. Satisfactory effects can be achieved
      with a combination therapy of chemotherapy and surgery.

Key words: postmenopausal women, choriocarcinoma, gestational trophoblastic tumor

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