中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2012, Vol. 41 ›› Issue (1): 14–17.

• 基础医学 • 上一篇    下一篇

基于小波变换的高强度聚焦超声消融兔VX2乳腺肿瘤声像图纹理分析

闵加艳1,邹建中1*,郭宇1,王冬2   

  1. (1.重庆医科大学生物医学工程学院,省部共建超声医学工程国家重点实验室,超声医学工程重庆市市级重点实验室,重庆 400016;2. 第三军医大学新桥医院超声科,重庆 400037)
  • 收稿日期:2012-09-19 修回日期:2012-09-19 出版日期:2012-01-01 发布日期:2012-09-21

Ultrasonogram Texture Analysis on Rabbit VX2 Breast Tumor HIFU Ablation Based on Wavelet Transform

Min Jia-yan1,ZOU Jian‐zhong1,Guo Yu1,Wang Dong2   

  1. (1.Chongqing Municipal?Key Laboratory of Ultrasound Engineering in Medicine, State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and MOST, College of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China;2.Department of Ultrasound, Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, China)
  • Received:2012-09-19 Revised:2012-09-19 Online:2012-01-01 Published:2012-09-21

摘要: 目的 探讨高强度聚焦超声(HIFU)治疗过程中多分辨率小波分析纹理参数对凝固性坏死的判断,提高超声监控判断凝固性坏死的灵敏度。方法 HIFU辐照在体新西兰大白兔VX2乳腺肿瘤,按辐照强度分为90 W、120 W、150 W 3组(每组40只),辐照时间均为3 s。采集辐照前后的声像图,通过小波变换提取声像图纹理参数,使用支撑适量机(SVM)建立决策平面,分析样本。结果 利用小波变换提取声像图纹理参数对HIFU消融组织凝固性坏死的判断高于灰度评价,且差异具有统计学意义(P

关键词: 高强度聚焦超声, 凝固性坏死, 纹理分析

Abstract: Objective To study the judging of coagulation necrosis by multi-resolution wavelet analysis texture parameters during the high intensity focused ultrasound (HIFU) treatment, to improve the sensitivity of judging coagulation necrosis by ultrasound monitoring. Methods The VX2 breast tumors of rabbits in three groups was irradiated for 3s, with a irradiating intensities of 90W, 120W, 150W, respectively, each group contained 40 New Zealand white rabbits; The ultrasonogram before and after irradiating were collected; Ultrasonogram texture parameters by wavelet transformation were extracted; Decision surfaces by means of support vector machine (SVM) was established; The samples were analyzed. Results Judging of coagulation necrosis of tissues ablated by HIFU by means of ultrasonogram texture parameters extracted by wavelet transformation was higher than that of gray scale evaluation, and the difference was of statistical significance (P

Key words: High intensity focused ultrasound, coagulation necrosis, texture analysis.

中图分类号: 

  • R445
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