中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2012, Vol. 41 ›› Issue (1): 87–90.

• 临床医学 • 上一篇    下一篇

股神经阻滞和关节内浸润控制前交叉韧带重建术后疼痛疗效比较的Meta分析

孙羽,白希壮1   

  1. (中国医科大学附属第一医院骨科,沈阳 110001)
  • 收稿日期:2012-09-19 修回日期:2012-09-19 出版日期:2012-01-01 发布日期:2012-09-21
  • 通讯作者: 白希壮.E-mail:zpmhh@sina.com
  • 作者简介:孙羽 (1984- ),男,助教,硕士.E-mail:sunyuloveit@163.com;

A Comparison of the Analgesic Efficacy of Femoral Nerve Block vs Intra-articular Injection for Anterior Cruciate Ligament Reconstruction — a Meta-analysis of Randomized Controlled Trials

SUN Yu, BAI Xi-zhuang   

  1. (Department of Orthopaedics, The First Hospital, China Medical University, Shenyang 110001, China)
  • Received:2012-09-19 Revised:2012-09-19 Online:2012-01-01 Published:2012-09-21

摘要: 目的 比较股神经阻滞(FNB)和关节内浸润(IA)治疗前交叉韧带重建术后疼痛的疗效。方法 计算机检索MEDLINE(1966至2011.6)、EMBASE (1980至2011.6)、Cochrane 图书馆,以及ClinicalTrials.gov网站,检索相关随机对照研究,利用Detsky分级对纳入文献作方法学评估,对可合并结果行Meta分析,无法合并结果作描述分析。试构建倒漏斗图分析发表偏倚。结果 共纳入5项随机对照试验,计437例患者。术后疼痛视觉模拟量表(VAS)评分Meta分析显示FNB镇痛优于IA,WMD -5.50 (-9.897, -1.14)。未能构建有意义的倒漏斗图。结论 现有证据表明FNB镇痛优于IA,但优势程度难以体现出实际临床意义。本分析仅纳入5项研究,病例较少,尚需多中心、大样本随机对照研究验证。

关键词: 术后镇痛, 股神经阻滞, 关节内浸润, 前交叉韧带重建, Meta分析

Abstract: Objective To compare the efficacy of femoral nerve block and intraarticular injection on relieving pain after anterior cruciate ligament reconstruction. Methods We searched electronic databases to identify randomized control trials, assessed methodological qualities and identified parameters for comparison. Meta-analysis was performed using Review Manager. Weighted mean difference was calculated for numerical data with 95% confidence interval. Heterogeneity was analyzed. Results 5 studies including 437 patients were identified. Meta-analysis of VAS with sensitivity analysis favored nerve block, WMD -5.50 (-9.897, -1.14). However, the effect may not be clinically significant. Conclusions Femoral nerve block might provide better pain relief, but the effect might not be clinically significant.

Key words: Key Words postoperative analgesia, femoral nerve block, intraarticular injection, anterior cruciate ligament reconstruction, meta-analysis.

中图分类号: 

  • R614.3
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