中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2012, Vol. 41 ›› Issue (5): 446–449.

• 临床医学 • 上一篇    下一篇

急性重症胰腺炎合并甲状旁腺功能亢进高钙危象的临床分析

刘维新,刘威羽,蔺虹名,周正,张庆敏   

  1. 中国医科大学附属第一医院消化内科,沈阳,110001
  • 收稿日期:2012-09-27 修回日期:2012-09-27 出版日期:2012-05-20 发布日期:2012-09-27

Clinical Study of Severe Acute Pancreatitis Complicated with Hypercalcemia Crisis in Hyperparathyroidism

LIU Wei-xin,LIU Wei-yu,LIN Hong-ming,ZHOU Zheng, ZHANG Qing-min.   

  1. Department of gastroenterology, The First Hospital, China Medical University, Shenyang 110001, China.Corresponding author:LIU Wei-xin,Email:weixinliu@yahoo.com
  • Received:2012-09-27 Revised:2012-09-27 Online:2012-05-20 Published:2012-09-27

摘要: 目的 单纯急性重症胰腺炎及单纯甲状旁腺功能亢进症高钙危象在临床上均是危重疾病,本文探讨重症胰腺炎并发甲状旁腺功能亢进症高钙危象临床表现、发病机制及诊治经验。方法: 回顾性分析急性重症胰腺炎合并甲状旁腺功能亢进症高钙危象患者的临床表现、实验室及影像学检查结果、治疗方法。结果:本文的4例患者在急性重症胰腺炎发病时血钙可降低或正常,恢复期监测离子过程中发现,血钙升高,考虑存在内分泌系统疾病,化验血清甲状旁腺激素并行超声定位,其中3例确诊为甲状旁腺瘤并均行手术切除,2例治疗痊愈,1例死亡,另一例未行手术治疗死亡。结论: 需注意胰腺炎并发甲状旁腺功能亢进症在临床表现、实验室检查及影像学特征方面的特异性,提高诊断,避免延误诊治。

关键词: 急性重症胰腺炎, 甲状旁腺功能亢进症, 高钙危象

Abstract: Objective Either severe acute pancreatitis or hypercalcemia crisis in hyperparathyroidism is a severe disease. The diagnosis is difficult and mortality is high in the patients with both conditions. Our aim was to study the clinical manifestations, mechanism, diagnosis and treatment of such cases. Methods A retrospective study was made on the clinical manifestations, results of laboratory and diagnostic tests and treatment of serve acute pancreatitis patients complicated with hypercalcemia crisis in hyperparathyroidism. Results At the attack of severe acute pancreatitis, blood calcium of four patients was lower or normal, while during the recovery, blood calcium increased, which indicates endocrine diseases. After being examined in PTH and ultrasonic or CT location, three cases were diagnosed as parathyroid adenoma and undergone resection. Two recovered, one died and another without operation also died. Conclusions Special attention should be paid to the clinical manifestations, results of laboratory and diagnostic tests and diagnosis of the patients with serve acute pancreatitis patients complicated with hyperparathyroidism.

Key words: serve acute pancreatitis, hyperparathyroidism, hypercalcemia crisis

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