中国医科大学学报

中国医科大学学报

中国医科大学学报 ›› 2013, Vol. 42 ›› Issue (10): 939–941.

• 短篇论著 • 上一篇    下一篇

1型糖尿病患儿血清可溶性肿瘤坏死因子相关凋亡诱导配体水平的变化及意义

苗静,辛颖   

  1. 中国医科大学附属盛京医院儿科,沈阳 110004
  • 收稿日期:2013-05-31 修回日期:2013-11-26 出版日期:2013-10-18 发布日期:2013-11-26
  • 作者简介:苗静(1986-),女,硕士研究生.辛颖,Email:xin.ying168@live.cn.

The Expression and Clinical Significance of Soluble Tumor Necrosis Factor-related Apoptosis-inducing Ligand level in Serumof Children with Type 1 DiabetesMellitus

  • Received:2013-05-31 Revised:2013-11-26 Online:2013-10-18 Published:2013-11-26

摘要:

检测初发1型糖尿病患儿血清sTRAIL、空腹血糖、糖化血红蛋白(HbA1c)和C肽水平,并进行相关性分析。结果显示:1型糖尿病患儿胰岛素治疗前、治疗3个月、6个月时血清sTRAIL水平显著低于正常对照组(P<0.05),治疗12个月时较治疗前明显上升,与对照组无显著差异。提示sTRAIL可能参与了儿童1型糖尿病的发病过程。

关键词: 肿瘤坏死因子相关凋亡诱导配体, 可溶性TRAIL, 1型糖尿病, 儿童

中图分类号: 

  • R725.8

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